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Chapter 2.  Miller’s Experiment And Other Origin Of Life Experiments

B. Setting the Stage: Miller’s Experiment

The chemicals used in and produced by living organisms tend to be different from those found
elsewhere in nature.  Among many other things, living systems are characterized by a prevalent
use of enzymes and proteins.  Enzymes and proteins are both made up of long chains of what are
called amino acids. Therefore, amino acids may properly be thought of as the building blocks of life.
See
Appendix A. Section 2. for a discussion on amino acid structure and Appendix A. Section 3. for
a discussion on enzyme
structure.

The simplest amino acid is called glycine. It is chemically equal to a molecule of vinegar combined
with a molecule of ammonia.  Glycine is inherently a simple chemical combination, yet it does not
form naturally and spontaneously anywhere on the earth apart from the action of living organisms.  
Besides glycine, there are 19 other amino acids coded for by the DNA in a living cell.  
How did physical life originate?  Is it truly a natural product of the normal laws of science?  Or, is it
the result of the creative efforts of a Living God?  Can the things we scientifically observe from
nature shed any light on these questions?

Most professors in most universities today are secular humanists. It has been this way for much of
the past 100 years.  A secular humanist believes that physical life formed as the natural result of
the normal laws of nature working over long periods of time.  He believes that these laws are
adequate to account for everything we observe around us today. He rejects any claims to the
existence of a Living God who has worked and still works within the domain of a creation that He
brought into existence.

However, the origin of life has always been a thorny problem for evolutionists and humanists.  The
kinds of chemicals appearing in living systems are frequently extremely complicated and are not
typical of those found outside of living systems.  Thus, these chemicals do not seem to appear
spontaneously. So, where did life come from?  

In 1953, a young graduate student at the University of Chicago named Stanley Miller appeared to
solve the problem. He assumed that the atmosphere on earth in the earliest days of its history
might have been similar to that of the planet Jupiter today.  Jupiter contains an atmosphere of
hydrogen, methane, ammonia, and water.  Jupiter also has large storms that produce lots of
lightning. So, Miller designed an experiment in which he mixed methane, ammonia, hydrogen, and
water in a spark chamber.  He then zapped the mixture with a spark. His experiment paralleled what
is taking place on Jupiter today.  His results startled the world.  He produced amino acids!    The
four simplest amino acids are called glycine, alanine, glutamic acid, and aspartic acid.   Miller
produced all four of these simple amino acids while running his experiment.  Altogether, about four
percent of the carbon that Miller introduced into the spark chamber was converted into these four
amino acids.

This experiment opened up a new branch of science, that of studying in a laboratory how life might
have formed on earth using various assumed initial conditions.  So, for instance, in the various
different experiments the initial, starting mixtures would sometimes contain formaldehyde, carbon
monoxide, or cyanide as well as some of the raw materials Miller used.  Different energy sources
such as ultraviolet light or even hot water were used.  

The results of running these experiments showed that some raw materials and energy sources
favored the formation of sugars. Others favored the formation of certain kinds of amino acids. Yet
others favored various components used in making RNA or DNA.  

Things seemed to be going well at first.  It seemed that there was some combination of energy and
raw materials that could be used to form almost any desired building block component for a living
cell. However, each one of the experiments, no matter what conditions were tested, invariably
reached dead ends.  After an initial period of excitement, very little new progress has been made in
this area during the last thirty years.  

One major problem was tar formation.  The various experiments tend either to produce nothing or
produce lots of tar.
1 However, they do not produce living cells, they do not produce enzymes.  They
do not produce RNA.  They do not even produce self-replicating molecules. Worst of all, they do
not even produce the hypothetical “pre-life soup” of a rich concentration of cellular building block
molecules.

This soup is typically presented as historical fact. However, even under the controlled conditions of
a laboratory where the most brilliant scientists in the world can manipulate conditions at will, no
satisfactory “soup” has ever been produced. Surprisingly enough, Miller’s original experiment is
actually the closest anyone has come to forming such a soup. This was due to the high amounts of
hydrogen he included in his initial atmosphere, but which has since been acknowledged to have
been unrealistic—hydrogen is so light that it very rapidly escapes earth’s gravitational pull and
becomes lost to outer space.  Miller’s experiment produced more products at closer to a usable
concentration than any that have followed after him. In Miller’s own words, talking in an October,
1996 interview about his early experiment, he said, “The surprise of the experiment was the very
large yield of amino acids. We would have been happy if we got traces of amino acids, but we got
around 4%. Incidentally, this is probably the biggest yield of any similar prebiotic experiment
conducted since then.”
2 So, no one has really improved on his original experiment. Yet, we shall
show that his products were not even close to providing an adequate starting point for the
formation of life.

It is amazing that when one cuts through all of the empty rhetoric about a pre-life soup that
evolutionists so proudly proclaim to be fact, he finds that there is essentially no substance to the
claims. After more than fifty years of effort, with lots of fame at stake for anyone who could be
successful, no scientist has ever been able to form a useful soup starting with reasonable pre-life
conditions of any kind. Talk about dead ends. No one has ever been able to improve on the results
of Miller’s original experiment.
All known experiments that start with raw, basic building block chemicals such as methane and
ammonia eventually run into dead ends.  No matter how long an experiment is allowed to run, it
never forms a soup with a useful concentration and useful variety of chemicals.  It forms either
nothing or it forms lots of tar.5  This is observation, consistent observation. This is what scientists
should present as the results of pre-life experiments.

It is our thesis that these dead ends are the inevitable result of the normal laws of science acting
normally.  The laws of science work against a natural formation of life, they do not promote it.  The
dead ends reached by these experiments are exactly what we would predict based on applying
certain basic principles of chemical behavior.  Hence, our predictions are confirmed by experiment.  
Science teaches that a natural origin of life is impossible.     

We will discuss many of these problems which lead to dead ends in our section on the 16 Fatal
Roadblocks Against A Natural Origin Of Life.

First though, for the sake of the discussion, it will help to have a reference point.  We will use Miller’
s experiment as that reference point.    

Most of the essential products necessary to form a living cell were NOT produced by Miller’s
experiment.  Although various other experiments were able to  produce some of the missing
products,  these other experiments invariably gave smaller yields than did Miller’s, both in
concentration of product formed and in the number of different products produced.  Hence, for our
discussion, we will focus on Miller’s experiment.  It is the best known of all similar experiments, its
results are readily available with a simple Internet search, and it gave the best results.  

I once was dialoging in an Internet discussion group with some people about these issues.  A
certain individual was constantly criticizing my use of Miller’s experiment.  He said he had in his files
copies of over 200 other experiments that he claimed gave better results than did Miller’s.  Much of
my discussion had featured certain mathematical calculations based on Miller’s results, similar to
what we will also be looking at later on in this pamphlet.  Finally, I challenged the individual to use
the results from any of these other 200 experiments, substitute them in the calculations, and show
how they invalidated any of the calculations or conclusions.  My claim was that it would not matter
which experiment he used as a basis for the calculations, he would still ultimately end up with
effectively the same results. The reason was that the results were due to underlying principles of
chemistry and that these principles were solid. Interestingly enough, he never brought up the issue
again.  It is these principles and calculations that we will present in our discussion of the sixteen
fatal roadblocks.