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© 2007  Creation Truth Outreach, Inc. All Rights Reserved.   This pamphlet may be freely copied provided it is copied in its entirety, its
contents are not altered in any manner, and additional or tighter copyright restrictions than these are not imposed on it.  
Revised May 5, 2008
Chapter 4. Limitations On Natural Selection.

5.  Natural Selection Works Best With Linear Genes, Not Stacked Ones.

Discussions on natural selection tend to assume a one-to-one relationship between genes and
enzyme sequences.  One gene controls one trait as an expression of the effects of one enzyme.  
Thus, a mutation to a particular gene may hopefully, occasionally give a survival advantage to
some  trait.

However, multi-cellular organisms do not have a one-to-one relationship between genes and
enzymes.  Instead, the sequence of codons in a gene defining a particular amino acid sequence
gets interrupted by what are called interons.  These represent control points in the DNA
information sequence which do not get decoded into amino acids.  The interons represent
boundaries between short segments of information that do get decoded.

Here is the catch.  A single gene in the DNA may actually be used to build half a dozen or so
different enzymes.  The different enzymes make use of different segments of information contained
within the same gene.  A specific enzyme gets assembled from the various segments by
specialized control enzymes.
23  For instance, it is now thought that human beings have only about
30,000 genes in their genome.  However, these 30,000 genes code for perhaps 100,000 different
enzymes.  That is an overall average of 3 different enzymes per gene.
24 Normally, no enzyme
uses all the segments. The choice of segments determines the structure and usage.

The problem is that a mutation that might supposedly be beneficial for the structure of one enzyme
could be harmful to the others formed from the same gene.   

It is hard enough to get a beneficial mutation to begin with. Experiments with fruit flies during the
1950s did not give observable evidence of a single known beneficial mutation.  Yet, multiple
thousands of harmful ones were observed.   

As a result of this situation, it is not enough for a mutation to somehow be of benefit in the changes
it makes to a particular enzyme.  The ripple-effect changes to the other enzymes built from the
same code segments must not harm them lest any advantage to the first quickly becomes lost.  If
one thinks his way through how enzymes are actually formed, with various coils and sheets pieced
together in an exactly prescribed manner, he can realize the difficulties in changing the shape of
one enzyme without changing the shape of another enzyme when both use the same segment of a
common gene.

Of course, as a creationist, I believe that this extraordinary complexity of the code was placed there
by a Creator.  He let us find out about it so that we may be in awe of His extreme intelligence and
wisdom.   

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